Neurodegeneration With Brain Iron Accumulation

Neurodegeneration With Brain Iron Accumulation

An Overview

Neurodegeneration with brain iron accumulation (NBIA) is a rare, genetically-linked disease which is characterized by the abnormal accumulation of iron in the brain. Those with this disease have progressive neurological degeneration of the nervous system. In some forms of NBIA, patients may have cognitive decline. However, more commonly, it presents with dystonia, dysarthria, choreoathetosis, ataxia, muscle rigidity and coordination related symptoms.

Risk Factors

From birth
Inherited disorder

Signs & Symptoms

The following are the symptoms to watch for in order to detect the disease early:
Dystonia (slow writhing, distorting muscle contractions of the limbs, face, or trunk)
Choreoathetosis (involuntary, purposeless jerky muscle movements)
Muscle rigidity (uncontrolled tightness of the muscles)
Ataxia (inability to coordinate movements)
Seizures
Spasticity (sudden, involuntary muscle spasms)
Confusion
Stupor
Visual changes
Dysarthria (slurred or slow speech)
Dementia

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Genetic Screening Limitations

Genetic screening can indicate whether an individual has a predisposition, or is at an increased likelihood, of having an inherited disease or disorder. However, it cannot indicate if the individual will show symptoms, how severe the symptoms will be, or whether the disease or disorder will progress over time.

A negative test result does not mean that an individual will not get an inherited disease or disorder because Qodify Genetic Screening tests are designed to detect only highly significant genetic markers which have been documented during medical research. Environmental and lifestyle factors also play a role in the development of inherited diseases, disorders, and even traits. In addition, the Qodify carrier test results are not intended to inform an individual of any risks for developing a disease, the health of the unborn child, or the child’s risk of developing the disease.

The results generated from Qodify genetic screening tests, which includes all additional health related information, is meant for informational purposes only and not an indicator of an individual’s current or future health status, nor a diagnosis for any disease, disorder, condition or other health issues. The information provided in the test results should be confirmed with a doctor or a healthcare professional in a clinical setting before any further action is to be taken – including the treatment, and type and quantity of prescription medicines to be taken (even if indicated in the drug response test results).

Healthpro Marketing Sdn Bhd does not guarantee or warrant the recommendation, diagnosis, therapy, treatment, medication, device, action or strategy of any individuals with relation to our genetic screening test results or any part of our website content. The recommendation given in the test results is for informational purposes only and is not intended as a substitute for, nor does it replace any professional medical advice, diagnosis, or treatment. It is advisable not to avoid, disregard or delay seeking and obtaining medical advice from qualified healthcare providers due to information which may have been obtained from any Qodify genetic screening test results.

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Genetic screening can indicate whether an individual has a predisposition, or is at an increased likelihood, of having an inherited disease or disorder. However, it cannot indicate if the individual will show symptoms, how severe the symptoms will be, or whether the disease or disorder will progress over time.

A negative test result does not mean that an individual will not get an inherited disease or disorder because Qodify Genetic Screening tests are designed to detect only highly significant genetic markers which have been documented during medical research. Environmental and lifestyle factors also play a role in the development of inherited diseases, disorders, and even traits. In addition, the Qodify carrier test results are not intended to inform an individual of any risks for developing a disease, the health of the unborn child, or the child’s risk of developing the disease.

The results generated from Qodify genetic screening tests, which includes all additional health related information, is meant for informational purposes only and not an indicator of an individual’s current or future health status, nor a diagnosis for any disease, disorder, condition or other health issues. The information provided in the test results should be confirmed with a doctor or a healthcare professional in a clinical setting before any further action is to be taken – including the treatment, and type and quantity of prescription medicines to be taken (even if indicated in the drug response test results).

Healthpro Marketing Sdn Bhd does not guarantee or warrant the recommendation, diagnosis, therapy, treatment, medication, device, action or strategy of any individuals with relation to our genetic screening test results or any part of our website content. The recommendation given in the test results is for informational purposes only and is not intended as a substitute for, nor does it replace any professional medical advice, diagnosis, or treatment. It is advisable not to avoid, disregard or delay seeking and obtaining medical advice from qualified healthcare providers due to information which may have been obtained from any Qodify genetic screening test results.

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